Worm Breeder's Gazette 8(2): 3
These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.
We are studying genomic organization in a small region around the unc-22 gene on linkage group IV. This region is approximately 1.5 map units in length and is defined by the deficiency, sDf2. In addition to the unc-22 gene, we have identified one other nonessential gene (dpy-20) and twenty essential genes that are uncovered by this deficiency. The mutations which defined these genes were positioned by two methods: recombination mapping relative to unc-22 and complementation mapping with the deficiencies. sDf7, sDf8, sDf9 and sDf10. The positions of the essential and nonessential genes in the sDf2 region are shown in the accompanying genetic map. Sixteen of the essential genes map in a 1.0-map unit region to the left of unc-22 whereas the remaining four essential genes are in a region of about 0. 5 map units to the right. Only eight of the twenty essential genes are represented by more than one allele. [See Figure 1]