CGC Bibliography Paper 5587

Metabolism and lifespan.

Van Voorhies WA

Medline:

Citation:

Experimental Gerontology 36: 55-64 2001

Type:

REVIEW

Genes:

Abstract:

There has recently been a great deal of scientific and popular interest in identifying the causes of aging. Currently one of the most popular mechanistic explanations for the aging process links the production of free radicals and other oxidants (often termed reactive oxygen species or ROS) produced during aerobic respiration to biomolecular damage that results in aging. While there is a large amount of correlative data supporting the importance of ROS to aging it remains to be determined if ROS are a primary cause of aging. It is essential to remember that aging is a complicated process which may have different causal mechanisms between different species and multiple causal mechanisms within species.